Getting Help with Treatment:-
No matter your diagnosis - the cancer stage, cell type, and location of the mesothelioma - getting specialized treatment from an experienced doctor will help you improve your prognosis and quality of life.
If you’d like to know more about how mesothelioma affects your life expectancy - and what you can do to improve yours - speak to a member of our Patient Help Team. We’re here to answer your questions and can even help connect you to an experienced mesothelioma doctor. Request a call from a team member today, or get a free copy of our mesothelioma help guide.
Emerging Treatments:-
Emerging treatments are developed and tested in clinical trials by medical researchers, doctors who find better ways to treat patients. If you’ve been diagnosed with stage–three or stage–four mesothelioma, you may not qualify for traditional treatments, like the EPP or a P/D. You may, however, benefit from emerging treatments researchers are testing in clinical trials. Some of these treatments include immunotherapy, gene therapy and photodynamic therapy.
Multimodal Therapy:-
Multimodal therapy is a combination of two or more treatment options, including surgery, chemotherapy, and radiation therapy. Overall, using more than one treatment has improved the life expectancy of patients with mesothelioma in any location, pleural or peritoneal.
According to a few recent studies, pleural mesothelioma patients who had an EPP combined with chemotherapy and radiation therapy experienced a median survival rate ranging from 13 to 23.9 months. Those who had a multimodal therapy combining P/D with chemotherapy and radiation therapy resulted in an even better survival rate of 30 months.
Cytoreduction with HIPEC is also a form of multimodal treatment. It’s a combination of surgery to remove tumours in the abdomen and heated chemotherapy applied directly to the abdominal cavity, which kills microscopic cancer cells after the procedure.
Life-Extending Treatment:-
Surgery
"Surgery is the most effective way for mesothelioma patients to extend their life expectancy. There are surgical options for pleural and peritoneal mesothelioma. If your doctor says you aren't eligible for surgical treatment, get a second opinion from another mesothelioma specialist."
There are two surgeries for patients with pleural mesothelioma are the extrapleural pneumonectomy (EPP) and the pleurectomy with decortication (P/D). A recent study reported that treatment with the EPP increased the overall survival rate of patients to about 27.5 months. The (P/D) —a less invasive procedure for patients with pleural mesothelioma — has produced results similar to the EPP, extending the survival rate of pleural mesothelioma patients to about 20 months.
Cytoreductive surgery with heated intraperitoneal chemotherapy (HIPEC) is the most effective surgical option for peritoneal mesothelioma. There are reports of patients increasing their life expectancy to greater than 7 years with this treatment.
Mesothelioma Location:-
The location of mesothelioma also has an effect on your life expectancy. Where the tumour originates — the lining of the lungs, abdomen, or heart - determines which treatment options are available to you.
Pleural mesothelioma originates in the lining of the lungs, the pleura. The average life expectancy for most patients with mesothelioma in this location ranges from 4 to 18 months. More life-extending treatment options are available for you if you’re diagnosed with pleural mesothelioma because doctors have more experience treating it. This type of mesothelioma accounts for 75 per cent of all diagnosed cases.
Peritoneal mesothelioma originates in the lining of the lungs, the peritoneum and has the best life expectancy. The average life expectancy for patients diagnosed with peritoneal mesothelioma is 12 months, though several studies have shown that having cytoreduction with HIPEC has extended the life expectancy of some patients to 5 years and beyond.
Pericardial mesothelioma originates in the protective lining of the heart, the pericardium. It’s rare, accounting for about 1 per cent of all diagnoses. The life expectancy for patients with pericardial mesothelioma is 6 months. Pericardial mesothelioma has limited treatment options because its rarity has given doctors a few opportunities to develop new treatments.
Cell Type:-
Mesothelioma cell type has a huge impact on your life expectancy. There are three cell types: epithelioid, sarcomatoid, and biphasic. Each cell type behaves - and responds to treatment - differently. Doctors determine the cell type of a tumour when they diagnose you. Identifying the cell type helps them create the most effective course of treatment for your diagnosis.
Epithelioid cells are egg-shaped and stick to each other as they spread. As a result, they spread slowly, making epithelioid mesothelioma the most treatable cell type with the best prognosis. The average life expectancy of a patient with epithelioid mesothelioma ranges from 12 to 27 months.
Sarcomatoid cells are spindle-shaped and spread quickly to other parts of the body - their speed makes them less responsive to treatment. The average life expectancy of a patient with sarcomatoid mesothelioma ranges from 7 to 18 months.
Biphasic tumours are made up of both epithelioid and sarcomatoid cells. The ratio of the two cell types determines the effect a biphasic mesothelioma tumour will have on your life expectancy. More epithelioid cells result in a longer life expectancy because epithelioid cells spread slowly and respond better to treatment. The average life expectancy of a patient with biphasic mesothelioma ranges from 8 to 21 months.
Written By:- Link
No matter your diagnosis - the cancer stage, cell type, and location of the mesothelioma - getting specialized treatment from an experienced doctor will help you improve your prognosis and quality of life.
If you’d like to know more about how mesothelioma affects your life expectancy - and what you can do to improve yours - speak to a member of our Patient Help Team. We’re here to answer your questions and can even help connect you to an experienced mesothelioma doctor. Request a call from a team member today, or get a free copy of our mesothelioma help guide.
Emerging Treatments:-
Emerging treatments are developed and tested in clinical trials by medical researchers, doctors who find better ways to treat patients. If you’ve been diagnosed with stage–three or stage–four mesothelioma, you may not qualify for traditional treatments, like the EPP or a P/D. You may, however, benefit from emerging treatments researchers are testing in clinical trials. Some of these treatments include immunotherapy, gene therapy and photodynamic therapy.
Multimodal Therapy:-
Multimodal therapy is a combination of two or more treatment options, including surgery, chemotherapy, and radiation therapy. Overall, using more than one treatment has improved the life expectancy of patients with mesothelioma in any location, pleural or peritoneal.
According to a few recent studies, pleural mesothelioma patients who had an EPP combined with chemotherapy and radiation therapy experienced a median survival rate ranging from 13 to 23.9 months. Those who had a multimodal therapy combining P/D with chemotherapy and radiation therapy resulted in an even better survival rate of 30 months.
Cytoreduction with HIPEC is also a form of multimodal treatment. It’s a combination of surgery to remove tumours in the abdomen and heated chemotherapy applied directly to the abdominal cavity, which kills microscopic cancer cells after the procedure.
Life-Extending Treatment:-
Surgery
"Surgery is the most effective way for mesothelioma patients to extend their life expectancy. There are surgical options for pleural and peritoneal mesothelioma. If your doctor says you aren't eligible for surgical treatment, get a second opinion from another mesothelioma specialist."
There are two surgeries for patients with pleural mesothelioma are the extrapleural pneumonectomy (EPP) and the pleurectomy with decortication (P/D). A recent study reported that treatment with the EPP increased the overall survival rate of patients to about 27.5 months. The (P/D) —a less invasive procedure for patients with pleural mesothelioma — has produced results similar to the EPP, extending the survival rate of pleural mesothelioma patients to about 20 months.
Cytoreductive surgery with heated intraperitoneal chemotherapy (HIPEC) is the most effective surgical option for peritoneal mesothelioma. There are reports of patients increasing their life expectancy to greater than 7 years with this treatment.
Mesothelioma Location:-
The location of mesothelioma also has an effect on your life expectancy. Where the tumour originates — the lining of the lungs, abdomen, or heart - determines which treatment options are available to you.
Pleural mesothelioma originates in the lining of the lungs, the pleura. The average life expectancy for most patients with mesothelioma in this location ranges from 4 to 18 months. More life-extending treatment options are available for you if you’re diagnosed with pleural mesothelioma because doctors have more experience treating it. This type of mesothelioma accounts for 75 per cent of all diagnosed cases.
Peritoneal mesothelioma originates in the lining of the lungs, the peritoneum and has the best life expectancy. The average life expectancy for patients diagnosed with peritoneal mesothelioma is 12 months, though several studies have shown that having cytoreduction with HIPEC has extended the life expectancy of some patients to 5 years and beyond.
Pericardial mesothelioma originates in the protective lining of the heart, the pericardium. It’s rare, accounting for about 1 per cent of all diagnoses. The life expectancy for patients with pericardial mesothelioma is 6 months. Pericardial mesothelioma has limited treatment options because its rarity has given doctors a few opportunities to develop new treatments.
Cell Type:-
Mesothelioma cell type has a huge impact on your life expectancy. There are three cell types: epithelioid, sarcomatoid, and biphasic. Each cell type behaves - and responds to treatment - differently. Doctors determine the cell type of a tumour when they diagnose you. Identifying the cell type helps them create the most effective course of treatment for your diagnosis.
Epithelioid cells are egg-shaped and stick to each other as they spread. As a result, they spread slowly, making epithelioid mesothelioma the most treatable cell type with the best prognosis. The average life expectancy of a patient with epithelioid mesothelioma ranges from 12 to 27 months.
Sarcomatoid cells are spindle-shaped and spread quickly to other parts of the body - their speed makes them less responsive to treatment. The average life expectancy of a patient with sarcomatoid mesothelioma ranges from 7 to 18 months.
Biphasic tumours are made up of both epithelioid and sarcomatoid cells. The ratio of the two cell types determines the effect a biphasic mesothelioma tumour will have on your life expectancy. More epithelioid cells result in a longer life expectancy because epithelioid cells spread slowly and respond better to treatment. The average life expectancy of a patient with biphasic mesothelioma ranges from 8 to 21 months.
Written By:- Link
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